In 1912, the University of California, Berkeley, became the first university in the nation to form a separate Department of Genetics. The first two appointments in the department went to plant geneticists Ernest Brown Babcock and Roy E. Clausen, and as the department grew slowly, shifting slightly away from its roots in agricultural science, it gained a strong reputation as an important center for research in several areas in genetics and evolutionary biology. The U.C. Berkeley Department of Genetics Collection contains a selective sampling of correspondence relating to the organization and early history of the nation's first Department of Genetics. Centered in the years 1912-1930, the collection consists primarily of correspondence to and from Babcock and Clausen, pertaining to their research, administrative matters, and the genetical community. Prominent among their correspondents are George H. Shull, Thomas Hunt Morgan, A. H. Sturtevant, and H. J. Muller.

The historian of science Robert C. Olby is a graduate of University College London and Oxford. Best known for his work on the history of genetics, especially the Bateson school, and for his study of the early history of molecular biology, Olby is currently a Research Professor in the History and Philosophy of Science at the University of Pittsburgh. He is the author of The Origins of Mendelism (1966), Charles Darwin (1967), The Path to the Double Helix (1974), and the Norton History of Biology. His current research is focused on the conceptual foundations of modern sensory neurophysiology and an intellectual biography of Francis Crick. The Olby Collection contains about 150 photocopies of correspondence and documents collected by Olby during research for The Path to the Double Helix. Among these is a copy of a manuscript by F. C. Crick and James D. Watson, "The Complementary Structure of Deoxyribonucleic Acid," prepared while Watson was at CalTech.

This miscellaneous collection relates to numerous topics in genetics: cattle breeding (especially the American Jersey Cattle Club), longevity, radiation, International Congress of Genetics (the 10th, 11th, and 13th), Gregor Mendel, aid for refugee scientists, and the records of the Genetics Society of America (1947-1974). The photographs series accession # 1968 433pr, was added to the finding aid in 2016.

A botanist and historian of science at the University of Pennsylvania, Conway Zirkle published on the history of evolutionary thought and genetics, with a particular interest in the discipline as practiced in the Soviet Union. The Zirkle Papers consist of approximately one linear foot of materials accrued by Zirkle during research for his book on Lysenko-era biology in the Soviet Union, The Death of Science in Russia (1949). Among the miscellaneous materials in the collection are four volumes (0.5 linear feet) of pressed specimens of ferns and algae.

Arthur J. Cain is an evolutionary biologist whose research interests have included genetics, natural selection, biogeography, and systematics. Based at Oxford University and, later, the University of Liverpool, much of Cain's research was field-based, focusing on terrestrial gatsropods. This collection contains correspondence, grant applications, reports, programs for scientific meetings, unpublished papers and lectures, research notes, charts, graphs, maps, and manuscript reviews of journal articles and books. The Cain Papers is divided into three series: I. Correspondence ; II. Subject Files ; and, III. Papers by Colleagues. Arrangement is alphabetical by folder title, and chronological within each folder.

The correspondence in this collection concerns behavior genetics, evolution, heredity, etc. There is material relating to the congresses of the Permanent International Committee on Genetics, and the IXth (Bellagio, 1953), Xth (Montreal, 1958), and XIth (The Hague, 1963) International Congress of Genetics. There is also correspondence pertaining to the Cold Spring Harbor Symposium on Quantitative Biology (1955), the Mendel Semi-Centennial Symposium (1950), the Soviet geneticists' visit to the U.S. in 1967, and to Anton R. Zhebrak.

A geneticist and educator, Philip Macdonald Sheppard was head of the Department of Genetics at the University of Liverpool from 1963-1976. His research centered on polymorphism, mimicry, blood groups, genetic disease, and speciation, using a variety of subjects, including the gastropod Cepaea nemoralis, butterflies, and humans. He may be best remembered for his classic study of industrial melanism in the pepper moth Biston betularia. The Sheppard Papers (1911-1983; bulk dates, 1940-76) contain correspondence, subject files, notes, and manuscripts that document Sheppard's life as a geneticist. The earliest piece in the collection is a lepidopterist's notebook from 1911, possibly J. R. Hobhouse's, however the bulk dates from 1940 to 1976, Sheppard's most productive and influential years. Among other things, these materials document Sheppard's research on the Scarlet Tiger moth, swallowtail butterflies, and ABO blood groups in humans, as well as his position as head of the Department of Genetics at the University of Liverpool.

Sewall Wright ranks among the most influential figures in the field of population genetics during the 20th century, and made important contributions to biostatistics, biometrics, and evolutionary theory. These papers contain much of Wright's professional correspondence, scattered research notes, and drafts of a small number of papers.

The Papers of Curt Stern include extensive correspondence, lectures (1920s-1970s, 1.5 boxes), autobiographical material, articles, zoological course notes, photographs, etc. Stern's various areas of scientific interest are documented in the collection: the chromosome theory of heredity, role of gene mutation and chromosome rearrangements in evolution, action and interaction of genes during individual development, and particularly his contribution to the development of human genetics as a discipline (centered on his popular and influential book, Principles of Human Genetics, 1949, 1960, 1973). Both his career in Germany and the United States is documented in his correspondence. After studying with T. H. Morgan at Columbia University on a Rockefeller Foundation Fellowship (1924-1926), Stern returned to Richard Goldschmidt's lab at the Kaiser-Wilhelm Institute (1926-1932). There is material of note in the collection concerning this period when Stern helped to establish the cytological basis of crossing over. After a short stay at the California Institute of Technology in 1932, Stern's temporary residence in the U. S. became permanent, and his later career at the University of Rochester, 1933-1947 (Chairman, Department of Zoology) and at the University of California, Berkeley, 1947-1970 (there is abundant material on the Department of Zoology) is covered in the collection. There is other material on: American Association for the Advancement of Science Inter-Society Committee on Science Foundation Legislation, 1946-1947; American Society of Human Genetics (Pres., 1957); Atomic Energy Commission (Advisory Committee for Biology and Medicine, 1950-1955); Genetics (journal); Oak Ridge National Laboratory (Advisory Committee for Biology, 1955-1968); and the Rockefeller Foundation. Stern's correspondence with friends and colleagues in Germany, England, and the U. S., during the 1920s-1930s, is of particular note as it documents not only the developments in genetics and the institutional and administrative networks supporting research, but it also offers general comments and observations on science, Germany, and politics. The photographs (2 boxes) include pictures of many prominent geneticists and scientists.